Marseille,Genoa,Civitavecchia,Messina,Valletta,Barcelona,Marseille

Marseille, gateway to Provence, is France's largest port and second largest city, with a vast history stretching back more than 2,000 years to its foundation by the Greeks in the 6th century BC. While much of the city is urban sprawl, it has a spectacular setting between dramatic limestone hills and the Mediterranean, and the once-industrial streets now feature stylish shops and cutting-edge art galleries, thanks to investment from its role as European Capital of Culture 2013. Most cruisers make a beeline for Le Vieux Port, a buzzing, picturesque harbour lined with boutiques, restaurants and cafes. This district attracts an eclectic crowd, from local fishermen to millionaires venturing ashore from James Bond-style mega-yachts. All gather to soak up Le Vieux Port's charming atmosphere, browse its bustling markets and tuck into a bowl of Marseille's classic signature dish, bouillabaisse (a rich fish stew).

The capital city in the land of Leonardo, Michelangelo and the popes is today a living museum with gorgeous artwork, amazing architecture and inspiring ancient sites. At the same time, it's alive and vibrant in a 21st-century way. It's an unforgettable city to visit, and we'll warn you right now that once you've experienced it, you'll want to go back for more.

One of our favorite things to do there is walk and ogle. On a recent visit, we took one day to do the route from Vatican City and St. Peter's Basilica -- with its jaw-dropping art, statuary, and religious significance -- to Via del Corso, where our quest for the latest Italian fashions was more than fulfilled amidst the well-dressed crowd of Roman shoppers. The next day, we went on an ancient history quest past ruins and columns, traversing the same streets Julius Caesar strode (and rode) to the Colosseum, where gladiators once battled. Walking on, we were awed by the Pantheon, the well-preserved ancient symbol of Rome and now a great hangout spot.

First-time visitors, many envisioning Rome as big and congested, will be surprised by the scenic layout, with its famous seven hills and the Tiber River running through the city. (Cleopatra famously made her grand entrance from the river.) And the senses may be shocked by the general energy, hustle and bustle. With cars, taxis and scooters roaring here and there, crossing the street can be a challenge. (Don't worry; there are quiet piazzas aplenty with lovely cafes where you can get away from it all and unwind.)

The food is, of course, wonderful -- we can't eat enough pasta -- and the spirit of la dolce vita (the good life) abounds. Whenever we do such a quest in Rome, we do regular gelato stops (try the yummy pine nut flavor) or coffee breaks. And the shopping scene serves up Prada, Gucci, Armani and more. (High style can be found in more affordable brands like Furla, as well.) What could be better than that?

No question, Rome has one of the world's most important collections of once-in-a-lifetime sights to see, including St. Peter's Basilica and the Sistine Chapel, the Colosseum, the Pantheon, the Forum and on and on and on. And for those historic monuments alone, the city is worth a visit.

But if you're on an itinerary where Rome is just a port of call for the day, you won't see everything. Either resign yourself to that fact, or book a tour that will at least drive you by the main sights. Be aware the port for Rome, Civitavecchia, is about 1.5 to 2 hours from the city. (There is decent train service.) If you're beginning or ending your cruise there, plan to stay at least a couple of nights to explore the Eternal City; it's likely to steal a piece of your heart. Make sure to drop a coin in Trevi Fountain, which is said to assure you'll come back again.

Messina is Sicily's most important city and port on the north east coast. From here you can take a tour to Taormina, a beautiful city overlooking Mount Etna. Visit the Palazzo Corvaia which dates from the l5th Century and the acoustically perfect Greek Theatre offering outstanding views of the Sicilian countryside.

Sailing into Valletta, Malta, is akin to stepping into the pages of a J.R.R. Tolkien fantasy; once you are in the protected harbour, it feels as though modern civilization has disappeared. Oh, you can see a car or two driving on the winding streets amid the limestone battlements, crenelated castles and hillside structures, but they seem terribly out of place and unexpected. Never mind that Malta, which owns 7,000 years of intriguing history, is fully modernized and contemporary. What you see when entering Valletta Harbour are the formidable defensive stone battlements of forts pockmarked by war guarding the strategic waterway. Cream-colored buildings and ancient church steeples grow out of the twisting streets and hillsides. In the bay and channels, Malta's colourful luzzo boats, fishing craft resembling an elf's shoe, ply the waters in the wake of modern giant cruise ships and tankers. Valletta was built by the Knights of St. John as a place to take care of wounded soldiers and pilgrims during the Crusades in the 16th century. Its unique landscape and ancient buildings have appeared in films such as "Troy," "Gladiator," "Captain Phillips" and "World War Z." This tiny Mediterranean country is part of an archipelago of five islands, only three of which are inhabited. Cruise ships visit the island of Malta and the port of Valletta (designed by a colleague of Michelangelo). Malta has been inhabited since 5000 B.C. and was colonized by the Phoenicians in 1000 B.C. Then, the islands went in turn to the Greeks, Carthaginians, Romans, Byzantines, Arabs, Normans and the Spanish, who handed them over to the Knights of the Order of St. John in a "perpetual lease" in 1533; this lasted until Napoleon seized control in 1798. The Maltese did not like the French, however, and rebelled by seeking aid from Great Britain; Malta became a British protectorate in 1800 and a part of the British Empire in 1814. Later, it shook off the British, as well, and was granted independence in 1964. Since 1974, Malta is a republic under the British Commonwealth. The influence of all of these cultures is evident in Malta, with the Roman period seemingly taking precedence.

Relax and enjoy the facilities and entertainment onboard your ship. If the weather is good take some sun and sunbathe on the pool deck. Otherwise explore below deck the wide range of activities that will be available during the day. Perhaps you prefer to find a quiet spot and catch up on your reading.

The capital of Spain's Catalonia region is one of the country's -- maybe even Europe's -- most beautiful and vibrant places. A city of contrasts, it is like no other in Spain; this is most evident in its architecture, a marriage of Gothic spikes and modern curves. (One name to keep an eye out for is Antoni Gaudi, Barcelona's most famous architect.) Barcelona is also a city of distinct neighbourhoods. The old city -- Ciutat Vella -- is the heart of everything, with museums, shopping and cafes. Then there's the port area, Port Vell, which features bars, restaurants, shops, an IMAX theatre and the largest aquarium in Europe. (Port Vell is different from the working port area where cruise ships dock, but it's not too far away.) Enchanting and ancient, the Barri Gotic (Gothic Quarter) is the centre of the old city and brings together the best of Barcelona in a series of narrow streets, shops, cafes and magical corridors. One of Barcelona's best attributes is that while it seems large and spread out, its neighbourhoods are surprisingly walkable and easily accessible by bus, metro or even on foot (in comfortable shoes). Don't miss a stroll along Las Ramblas, replete with produce and flower stands, a historic opera house and maybe even a glimpse of Marilyn Monroe calling to you from the balcony of the Erotica Museum. Just be sure to rest your feet now and then over a few plates of tapas (which are meant to be shared, but we won't tell if you don't) and an ice-cold pitcher of sangria or a bottle of cava, the region's sparkling wine.

Marseille, gateway to Provence, is France's largest port and second largest city, with a vast history stretching back more than 2,000 years to its foundation by the Greeks in the 6th century BC. While much of the city is urban sprawl, it has a spectacular setting between dramatic limestone hills and the Mediterranean, and the once-industrial streets now feature stylish shops and cutting-edge art galleries, thanks to investment from its role as European Capital of Culture 2013. Most cruisers make a beeline for Le Vieux Port, a buzzing, picturesque harbour lined with boutiques, restaurants and cafes. This district attracts an eclectic crowd, from local fishermen to millionaires venturing ashore from James Bond-style mega-yachts. All gather to soak up Le Vieux Port's charming atmosphere, browse its bustling markets and tuck into a bowl of Marseille's classic signature dish, bouillabaisse (a rich fish stew).